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Molecular basis of enzyme action

Вибіркова дисципліна для ОП

Second

2023/2024

9 Semester

3

PR03. Use theories and laws of mathematics, physics, chemistry and other sciences to solve problems of modern biology. PR04. Understand the basic terms, concepts, principles, theories and laws in the field of biological sciences and on the borders of subject areas PR05. Use knowledge and demonstrate compliance with the provisions of biological ethics, biological safety and biological protection. PR08. Demonstrate knowledge of fundamental biological processes, structure and functions of living organisms. PR15. Apply in professional activities methods for determining the structural and functional characteristics of biological systems at different levels of the organization. PR16. Choose methods, algorithms for planning and conducting field, laboratory, clinical and laboratory research, including mathematical methods and software for research, processing and presentation of results.

External form

1. Successful mastering of the courses "Bioorganic Chemistry", "Molecular Biology", "Biochemistry", "General Genetics", "Biotechnology". 2. Be able to independently apply knowledge of bioorganic chemistry, molecular biology, biochemistry, biotechnology, etc. disciplines, perform laboratory and practical work, work with scientific and methodological literature. 3. Have basic skills in working with materials and equipment used in biological and biotechnological laboratories.

The discipline "Molecular basis of enzyme action" includes the study of biochemical and molecular mechanisms of catalysis, modern theories of enzyme-substrate interaction, the relationship between the structure of active centers of enzymes and their catalytic activity, biochemical mechanisms of enzyme regulation. Peculiarities of enzymes functioning are studied, modern data on their structure are generalized, mechanisms of regulation of enzymatic activity are considered. Attention is paid to the applied aspects of the use of enzymes for the development of new drugs aimed at correcting numerous disorders of intracellular biochemical processes.

1. Kravchenko O.O., Savchuk O.M., Ostapchenko L.I. Basics of biotechnology. Tutorial. - K.: VOC KNU. - 2019 2. Trevor Palmer, Philip L. Bonner ENZYMES: Biochemistry, Biotechnology and Clinical Chemistry Second Edition Published by Woodhead Publishing Limited, 2007, P. 431

Lecture, independent work

Semester assessment: 1. Modular test 1 (remote) - PH 1.1; 1.2. - 20 points / 10 points 2. Modular control work 2 - PH 1.3; 1.4 - 20 points / 10 points 3. Test work - PH 2.1; 3.1 - 20 points / 10 points Final assessment: in the form of an exam

Ukrainian