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Genetic bases of biotechnological processes

Обов’язкова дисципліна для ОП

First

2023/2024

5 Semester

4

PR06. Be able to determine and analyze the basic physicochemical properties of organic compounds that are part of biological agents (proteins, nucleic acids, carbohydrates, lipids). PR11. To be able to carry out basic genetic and cytological studies to improve and increase the biosynthetic capacity of biological agents, taking into account the principles of biosafety, biosecurity and bioethics (induced mutagenesis using physical and chemical mutagenic factors, selection and accumulation of auxotrophic mutants, transfer of genetic information, etc.)

Full-time form

1. Successful mastering of courses that cover basic issues related to such areas as molecular biology, biochemistry, cytology. 2. Knowledge of basic theoretical foundations of genetics, biochemistry, embryology, molecular biology. 3. Ability to independently apply knowledge of chemistry, general biology and other disciplines, use a computer, work with scientific literature.

The course is devoted to modern ideas about the mechanisms of heredity and variability. Significant emphasis is placed on the application of knowledge of classical and molecular genetics in biotechnological processes. The basic principles of inheritance of monogenic and polygenic traits, molecular genetic mechanisms of trait variability, features of the organization of the genetic apparatus and the course of genetic processes in viruses, prokaryotes, unicellular and multicellular eukaryotes, much attention is paid to human genetics. In the course of studying the discipline the practical application of genetics methods in biotechnology is given or demonstrated. Special emphasis is placed on the methods of genetic engineering, genetic therapy and the connection between genetics and biotechnology.

1. "Laboratory Workshop on Genetics". For students of the Faculty of Biology / order. Afanasyeva KS, Rushkovsky SR, Bezrukov VF, Demidov SV - Kyiv: Phytosocial Center, 2010 2. Sivolob AV, Rushkovsky SR, Kiryachenko SS, Afanasieva KS, Bezrukov VF, Kozeretskaya IA, Demidov SV Genetics - Kyiv: University of Kyiv, 2008. 3. Fedorenko VO, Chernik YI, Maximov DV etc. Problems and exercises in genetics Lviv .: Oriana-Nova Publishing House, 2008,

Lectures, laboratory classes, independent work

Semester assessment: 1. Modular test work1: PH 1.1, 1.3, 2.1, 2.3– 35 points / 15 points 2. Modular test work 2: PH 1.2, 1.3, 2.2, 2.3– 30 points / 15 points 3. Solving practical problems: RN 2.1 - 3.1 - 15 points / 7.5 points 4. Execution and protection of laboratory works: РН 1.1, 1.2, 2.1 - 3.1 - 10 points / 5 points 5. Evaluation of additions and answers: RN 1.1 - 3.1 - 10 points / 5 points Final assessment: in the form of a credit

Ukrainian