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Structure and functions of nucleic acids

Вибіркова дисципліна для ОП

First

2023/2024

6 Semester

3

PR08. Know and understand basic terms, concepts, theories and laws in the field of biological sciences and on the border subject areas. PR11. Understand the structural organization of biological systems at the molecular level. PR13. Know the mechanisms of preservation, implementation and transfer of genetic information and their significance in evolutionary processes. PR19. Apply methods in practical activities definition of structural and functional characteristics of biological systems at different levels organizations PR24. Analyze physical and chemical properties and the functional role of biological macromolecules and molecular complexes of living organisms, the nature of their interaction with ions, molecules and radicals, their structure and energetics of processes. PR25. Solve specific applied problems biology by appropriate methods

Full-time form

1 Successful mastering of courses ("General Cytology", "Histology", "Bioorganic Chemistry", "Biochemistry", "Molecular Biology", "General Genetics"). 2. Be able to independently apply knowledge of molecular biology, biochemistry, etc. disciplines, perform laboratory and practical work, work with scientific and methodological literature. 3. Have basic skills in working with materials and equipment used in biological and biotechnological laboratories.

"Structure and functions of nucleic acids" is a discipline that examines the structural features of different types of DNA and RNA, the participation of these molecules in cell function at the molecular level, the organization and regulation of chromatin as a hereditary material, as well as mechanisms and regulation nucleic acid metabolism. Particular attention is paid to modern methods of studying the biochemistry and molecular biology of DNA and RNA, namely - methods of isolation, purification, identification of nucleic acids, qualitative and quantitative reactions to DNA and RNA and their components, methods of studying the structure and function of nucleic acids polymerase chain reaction, blotting, electrophoresis in agarose and other gels, determination of the expression of certain genes, etc.

1. Berg, J. M., Biochemistry. Freeman, 7th edition, 2011. 2. Lodish, H., Berk, A..Baltimore, D. and James Darnell, J. Molecular Cell Biology ; Freeman, 7th edition 2013. Nelson, D. L. & Cox, М. М. Principles of Biochemistry. Freeman, 6th edition, 2013. 3. Остапченко Л.І. Гребіник Д.М. Біохімія нуклеїнових кислот. Навчальний посібник. - 2013. - 290 с. 4. Alberts, B., Johnson. A., Lewis, J. Raff, M., Roberts, K. and Walter P. Molecular Biology of the Cell. Garland Science, 6th edition 2014. 5. Stephen Niedle. Principles of nucleic acids structure. Elsevier, 2008. 302 p. 6. Mathews, C. K. & Van Holde, K. Е. & Ahern, K. G. Biochemistry. Addison Wesley. Ath edition, 2012. 7. Voet, D. & Voet, J. G. Biochemistry. дір edition, 2015.

Lecture, individual work

Semester assessment: 1. Modular control work I - PH 1.1; 1.2; 1.3 - 20 points / 10 points 2. Modular control work 2 - PH 1.4; 1.5; 1.6 - 20 points / 10 points 3. Testing - pH 2.1 - 10 points / 5 points 2. Presentation - PH 3.1 - 10 points / 5 points - final assessment: in the form of an exam

Ukrainian