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Methods of determining organic components and elemental composition of substances

ВКБ.3.08

Вибіркова дисципліна для ОП

First

2022/2023

8 Semester

3

P06 Understand the periodic law and the periodic system of elements, describe, explain and predict the properties of chemical elements and compounds based on them. P07 Apply the basic principles of quantum mechanics to describe the structure of atoms, molecules, and chemical bonds. P15 Ability to use acquired knowledge and skills for calculations, display and modeling of chemical systems and processes, processing experimental data. P18 Demonstrate knowledge and understanding of basic facts, concepts, principles and theories in chemistry. P21 Monitor and analyze scientific sources of information and professional literature.

Know the basics of inorganic, organic and physical chemistry, chemical and instrumental methods of quantitative analysis and the course "physical research methods in chemistry". Successful completion of basic courses in general chemistry, physics and mathematics at the undergraduate level.

As part of the course "Mass spectrometry and X-ray fluorescence in analysis", the physicochemical basics of the mass spectrometry (MS) method and its combination with previous methods of separation: gas and liquid chromatography are studied. Tandem mass spectrometry, laser desorption-ionization mass spectrometry, isotope ratio mass spectrometry, and inductively coupled plasma mass spectrometry approaches are also studied. The basics of X-ray fluorescence spectral analysis (XFRS), formation of an analytical signal, methods of qualitative and quantitative analysis are also studied. Peculiarities and practical nuances of the application of these methods are considered for solving a wide range of chemical and analytical problems: analysis of environmental objects, biomedical research and control of modern technological processes, etc.

1. O.V. Ishchenko, S.V. Gaidai, O.A. Byeda, Mass spectrometry., K.: Kyiv University. 2018. – 244 p. 2. A. Lebedev, Comprehensive Environmental Mass Spectrometry, ILM Publications, 2012. 3. J. H. Gross, Mass Spectrometry. A Textbook. 3rd Edition. Springer, 2017. 4. R. K. Boyd, C. Basic, R. A. Bethem, Trace Quantitative Analysis by Mass Spectrometry, John Wiley & Sons, 2008 5. K.M. Belikov, O.I. Yurchenko X-ray fluorescence analysis, Study guide, Kharkiv, 2012, 52 p. 6. R.M. Silverstein, F.X. Webster, D.J. Kiemle, D. L. Bryce, Spectrometric Identification of Organic Compounds, 8th Edition, Wiley 2014. 7. J. T. Watson, O. D. Sparkman, Introduction to mass spectrometry, Wiley 2007. 8. J. Greaves, J. Roboz, Mass Spectrometry for the Novice, Taylor & Francis, 2014.

Сombination of lectures and practical exercises

Semester control includes homework and tests. The evaluation is based on a 100-point scale. The maximum / minimum number of points that can be obtained by a student during the semester assessment is 60 points / 36 points. The final assessment is conducted in the form of an exam. The maximum / minimum number of points that can be obtained by a student in the exam is 40 points / 24 points.

Ukrainian