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Mechanisms of cell aging

Вибіркова дисципліна для ОП

Second

2022/2023

4 Semester

3

PLO 02. Understanding and knowledge of fundamental and clinical biomedical sciences, at a level sufficient for solving professional tasks in the field of health care. PLO 05. Collect complaints, anamnesis of life and diseases, ... (according to list 4)... PLO 07. Prescribe and analyze additional (mandatory and optional) examination methods (laboratory, functional and/or instrumental) (according to list 4)... PLO 27. Communicate freely in the national and English languages... PLO 28. Make effective decisions on health care problems... PLO 29. Plan, organize and carry out measures for the specific prevention of infectious diseases... PLO 30. Apply modern methods of cytological and histological analysis to determine the physiological status of a cell... PLO 31. Apply modern methods of clinical analysis to determine the physiological status of a cell... PLO 32. Form an analysis system and interpret new results...

Full-time form

1. Successful mastering of the academic disciplines "Human anatomy", "Physiology", "Histology, cytology and embryology", "Medical biology". 2. Ability to work independently with scientific and scientific-methodical literature. 3. Possession of elementary skills of system analysis.

The educational discipline "Mechanisms of cell aging" is a component of the educational program of professional training of specialists at the "Master's" educational level. The discipline program examines cell aging processes; the analysis of structural and functional changes of the organism at different levels of the living organization during the aging process of the organism is carried out; a causal analysis of the body's aging processes is carried out; possible ways of correcting the development of age-related changes in the body are considered.

1. Varenyuk, I., Dzerzhynskyi, M. (2013) Basics of gerontology and mechanisms of cell aging. Kyiv: Interservice 2. Behl, Ch., Ziegler, Ch. (2014) Cell Aging: Molecular Mechanisms and Implications for Disease. 2014th Edition. Springer. 3. Bell, C., Lowe, R., Adams, P., Baccarelli, A., Beck, S., Bell, J. & Rakyan, V. (2019). DNA methylation aging clocks: challenges and recommendations. Genome biology, 20(1), pp. 1-24. 4. Cellular Aging and Cell Death (1995) N. Holbrook, G. Martin, R. Lockshin, ed. 5. Chakravarti, D., LaBella, K. & DePinho, R. (2021). Telomeres: history, health, and hallmarks of aging. Cell, 184(2), pp. 306-322. 6. Ferrucci, L., Gonzalez‐Freire, M., Fabbri, E., Simonsick, E., Tanaka, T., Moore, Z. & de Cabo, R. (2020). Measuring biological aging in humans: A quest. Aging cell, 19(2), e13080.

Lectures. Practical training. Independent work.

Semester assessment: 1. Modular control work 1. 2. Modular control work 2. 3. Final modular control work. 4. Evaluation of practical works. 5. Survey of students in classes. The final assessment is in the form of a credit

ukrainian