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Biology of endoreduplication

Вибіркова дисципліна для ОП

First

2022/2023

10 Semester

3

PR04. Understand the basic terms, concepts, principles, theories and laws in the field of biological sciences and on the boundaries of subject areas. PR06. Apply the principles of taxonomy, methods of detection and identification of non-cellular life forms, prokaryotes and eukaryotes. PR07. Demonstrate knowledge of the structural organization of biological systems at the molecular level of the organization. PR09. Demonstrate knowledge of heredity and variability, molecular mechanisms of conservation and realization of genetic information and importance in evolutionary processes. PR15. Apply in professional activities methods for determining the structural and functional characteristics of biological systems at different levels of the organization. PR17. Through self-study to master new knowledge and modern methods of experimental research to solve problems of biology.

External form

1. Successful mastering of the courses "Molecular Biology", "Zoology", "Cytology", "Biochemistry", "Microbiology", "General Genetics". 2. Be able to independently apply knowledge of molecular biology, cytology, biochemistry, microbiology, etc. disciplines, perform laboratory and practical work, work with scientific and methodological literature. 3. Have basic skills in working with materials and equipment used in biological and molecular biological laboratories.

Endoreduplication is a set of processes that lead to the reproduction of genetic material (increase in DNA content) inside the cell. Forms of endoreproduction are endomitosis, polytenia, etc. The course examines the peculiarities of these processes in different organisms and in different cell types. Structure of polytene chromosomes of different species of organisms, methods of preparation and analysis of preparations of polytene chromosomes of different species of Drosophila, molecular methods of study of polytene chromosomes and use of polytene chromosomes in different areas of biological science.

1. Satarova T.M., Abraimova E.E., Vinnikov A.I., Cherenkov A.V. Plant biotechnology: [textbook]. Dnepropetrovsk: GU Institute of Grain Crops NAAS, 2016. - 136 p. 2. Zhimulev I.F. Morphology and structure of polytene chtomosomes. - 1996. - Advances in Genetics, vol. 34. - 497 p. 3. Van Steensel B. Chromatin: constructing the big picture// The EMBO Journal (2011) 30, 1885–1895

Lectures, independent work

Semester assessment: 1. Modular control work 1 (performed remotely) - PH 1.1; 1.2. - 30 points / 15 points 2. Modular control work 2 - PH 1.3; 1.4 - 30 points / 15 points 3. Express control works PH 2.1-2.2 - 10 points / 5 points. 4. Evaluation of oral answers, additions, solving research problems - PH 1.1-2.2 - 10 points / 5 points 5. Final test - PH 3.1 - 20 points / 10 points Final assessment: in the form of a credit

Ukrainian