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Molecular biology of viruses

Вибіркова дисципліна для ОП

First

2022/2023

10 Semester

3

PR03. Use theories and laws of mathematics, physics, chemistry and other sciences to solve problems of modern biology PR04. Understand the basic terms, concepts, principles, theories and laws in the field of biological sciences and on the borders of subject areas PR07. Demonstrate knowledge of the structural organization of biological systems at the molecular level of the organization PR09. Demonstrate knowledge of heredity and variability, molecular mechanisms of conservation and realization of genetic information and importance in evolutionary processes PR17. Through self-study to master new knowledge and modern methods of experimental research to solve problems of biology PR21.2. Apply basic knowledge, skills and abilities to identify and identify pathogens of viral diseases

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1. Know the theoretical foundations of virology, biochemistry, molecular biology, genetics. 2. Be able to independently apply knowledge of general virology, biochemistry, molecular biology, genetics.

The course "Molecular Biology of Viruses" covers the molecular aspects of replication strategies of viruses, including strategies for virus penetration into the cell, genome expression, assembly, release of DNA and RNA-containing viruses. Much attention is paid to key aspects of the interaction of viral and cellular components and their interaction on the end result of viral infections, unique mechanisms of antiviral cellular protection and viral response systems. Modern experimental approaches to the study of molecular mechanisms of virus reproduction and host-virus interactions are studied. Understanding the molecular mechanisms of virus-host interaction opens wide opportunities in the development of tools for the prevention and treatment of viral infections.

1. Andriychuk O.M., Koroteeva G.V., Molchanets O.V., Kharina A.V. Viral infections of humans and animals: epidemiology, pathogenesis, features of antiviral immunity, therapy and prevention / Taras Shevchenko National University of Kyiv VPC "Kyiv University", 2014-415p. 2. Virology. Textbook for laboratory studies / V.P. Polishchuk, I.G. Budzanovskaya, T.P. Shevchenko, E.M. Andriychuk, T.A. Kompanets, O.A. Kondratyuk, G.V. Koroteeva, O.V. Molchanets, A.V. Kharina, O.V. Shevchenko. - M.: TsP "Komprint", 2017. - 242 p. 3. Budzanovskaya I.G. and others. Virology.-K., Kyiv University, 2020.-347p. 4. Kharina A.V., Budzanovskaya I.G., Polishchuk V.P. Chemotherapy of viral infections. - K .: Phytosociocentr. - 2003. 117 p. 5. Flint SJ, Enquist LW, Krug R. M. Et al. Principles of virology: molecular biology, pathogenesis, and control. - Washington, D.C.: ASM Press. - 2000.

Lecture, independent work

Semester assessment: 1. Modular test 1 (remote): - PH 1.1 - 2.2 - 30 points / 15 points 2. Modular test work 2 - PH 1.1 - 2.2 - 30 points / 15 points 3. Presentations / reports, oral presentations, additions: PH 1.1 - 3.1 - 40 points / 20 points Final assessment: in the form of a credit

Ukrainian