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Molecular mechanisms of allergic reactions

Вибіркова дисципліна для ОП

First

2022/2023

9 Semester

3

PR04. Understand the basic terms, concepts, principles, theories and laws in the field of biological sciences and on the borders of subject areas PR07. Demonstrate knowledge of the structural organization of biological systems at the molecular level of the organization. PR12. Demonstrate knowledge of the structure and functions of the immune system, cellular and molecular mechanisms of immune responses, their regulation, genetic control; types of immunity and methods of assessing the immune status of the organism. PR22.4. Solve fundamental and applied problems in the field of immunology

External form

1. Successful mastering of the courses "Immunology", "Biochemistry", "Biotechnology", "Cytology", "Human Physiology and Anatomy". 2. Ability to independently apply knowledge of molecular biology, biochemistry, cytology, physiology, immunology, etc. disciplines, work with scientific and methodological literature. 3. Have basic skills in working with physico-chemical and biological research methods.

The course covers the molecular mechanisms of different types of hypersensitivity reactions. The course is based on the classification of different types of hypersensitivity by the mechanisms of immunopathogenesis. An important place is given to the peculiarities of the implementation of immune-mediated damage to tissues and organs, cellular and mediator mechanisms of immunopathological reactions in reagin, cytotoxic, immunocomplex inflammation, as well as the development of granulomatous reactions in various pathologies. Much attention is paid to the biochemical aspects of allergic inflammation, the participation of various pro-inflammatory and anti-inflammatory mediators in the interaction of immune cells and the role of immune cells in regulating homeostasis, unique features of immunoregulatory mechanisms in ensuring normal functioning.

1. Immunology. Textbook. / Edited by Pasteur E.U. / - Kyiv: Publishing and Printing Center "Kyiv University", 2011. - 911 p. 2. Immunology / Translation edited by prof. V.V.Chopyak - Vinnitsa: New BOOK, 2004. - 672p.

Lecture, independent work

Semester assessment: 1. Modular test 1 (remote): PH 1.2 - 1.5 –30/15 points; 2. Modular test work 2: PH 1.1 - 3.1 - 60/30 points; 4. Summary: РН1.2 - 3.1 - 10 points / 5 points. Final assessment: in the form of a credit

Ukrainian