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Synthesis of sp3-enriched cyclic systems

ВБ.4.02

Вибіркова дисципліна для ОП

Second

2022/2023

2 Semester

3

P1. Knowledge to understand scientific concepts and modern theories of chemistry, as well as the fundamentals of related sciences. P2. Deeply understand the basic facts, concepts, principles and theories related to the subject area mastered during the master's program, use them to solve complex problems and problems, as well as conduct research in the relevant field of chemistry. P4. Synthesize chemical compounds with specified properties, analyze them and assess compliance with specified requirements. P10. Plan, organize and conduct experimental research in chemistry using modern equipment, competently process their results and draw sound conclusions. P15. Possession of the general methodology of scientific research.

Full-time form

1. Know organic chemistry at the bachelor's degree in Chemistry. 2. Have skills in writing organic reactions. 3. Have an idea of stereochemistryat the bachelor's degree in Chemistry. 4. Have the skills to write the mechanisms of organic reactions at the bachelor's degree in Chemistry.

The methods of organic synthesis that allow the creation of sp3-enriched carbo- and heterocycles, the mechanisms of these reactions, and their stereochemical features are studied. Cyclization reactions and pericyclic reactions, methods of formation of alicyclic systems (cyclopropanes, cyclobutanes, cyclopentanes, cyclohexanes), pyrrolidines and other sp3-enriched heterocyclic systems are studied.

1) Modern methods of organic synthesis: textbook for students. chemical f-tu / O.O. Grygorenko, O.V. Shablykina – K.: VOC "Kyiv University", 2020. – 572 p. 2) W.A. Smith., A.F. Bochkov, R. Caple. Organic Synthesis – the Science behind the Art. Cambridge, 1998. – 477 p. 3) M. Smith. Organic Synthesis. 3rd Ed. Academic Press, 2011. – 1534 p. 4) March's Advanced Organic Chemistry:  Reactions, Mechanisms and Structure, 5th ed by M. B. Smith and J. March. – Wiley Interscience:  New York. 2001. – 2112 p.

Lectures

Evaluation is carried out on a 100-point system. Current control - homework, tests (maximum 60 points), exam (maximum 40 points)

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